Notice the 4 times the bible talks about focusing on "One Thing"
Behold the beauty of the Lord and inquire in His temple
Psalm 27:4 One thing I have desired of the Lord, That will I seek: That I may dwell in the house of the Lord all the days of my life, To behold the beauty of the Lord, and to inquire in His temple.
Notice the context is about not letting the fear of others distract you from God
Surrender all and follow Jesus
Luke 18:22 So when Jesus heard these things, He said to him, “You still lack one thing. Sell all that you have and distribute to the poor, and you will have treasure in heaven; and come, follow Me.”
Notice the context is about not letting riches distract you from God
Sit at Jesus' feet and hear His word
Luke 10:39-42 ...Mary... sat at Jesus’ feet and heard His word.... But Martha was distracted with much serving... And Jesus answered and said to her... one thing is needed, and Mary has chosen that good part, which will not be taken away from her.
Notice the context is about not letting service distract you from your dependence on God
Forget what's behind and press toward the goal
Philippians 3:13-14 Brethren, I do not count myself to have apprehended; but one thing I do, forgetting those things which are behind and reaching forward to those things which are ahead, I press toward the goal for the prize of the upward call of God in Christ Jesus.
Notice the context is about not letting the past distract you from God
Priorities and The Heart
Notice that in Matthew 6, Jesus basically tells us not to do things to get noticed (verses 1-18), not to be obsessed with gaining riches (verses 19-24), and not to worry about getting what we need (verses 25-33). God knows what we need and will provide it; all He asks of us is to focus on is His kingdom and His righteousness, living one day at a time.
Notice how Jesus says, "Lay up for yourselves treasures in heaven... For where your treasure is, there your heart will be also." Matthew 6:20-21. Whatever you value, whatever you set your affections on, is where your heart will be drawn to. We are to set our minds on things above, not on things on the earth (Colossians 3:2). When you read that in context you see this is connected with letting go of our old life "the old man and his deeds" and putting on the "new man", reflecting God's character in our relations with others.
20/20 Vision and Light to keep you from stumbling
Notice what Jesus says about having a good eye, that is to say, an eye that is focused: "The lamp of the body is the eye. If therefore your eye is good, your whole body will be full of light. But if your eye is bad, your whole body will be full of darkness. If therefore the light that is in you is darkness, how great is that darkness!" Matthew 6:22.
God's word is a light to our path and Jesus is the word in the flesh (Psalm 119:105, John 1:14). Jesus said, "If anyone walks in the day, he does not stumble, because he sees the light of this world." John 11:9. "I am the light of the world. He who follows Me shall not walk in darkness, but have the light of life." John 8:12
"The night is far spent, the day is at hand. Therefore let us cast off the works of darkness, and let us put on the armor of light. Let us walk properly, as in the day, not in revelry and drunkenness, not in lewdness and lust, not in strife and envy. But put on the Lord Jesus Christ, and make no provision for the flesh, to fulfill its lusts." Romans 13:12-14
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